A/Prof Stuart Ralph
Principal Research Fellow
Department of Biochemistry and Molecular BIology
The University of Melbourne
saralph@unimelb.edu.au
Research Activities
Stuart Ralph's research interests include the molecular and cell biology of apicomplexan parasites, particularly Plasmodium and Toxoplasma, and aspects of this biology that may be targeted by chemotherapeutic interventions. The Ralph lab conducts research using molecular, cell biological and bioinformatics techniques
Research Keywords
Researching in the following areas:
Plasmodium, Biochemistry, Bioinformatics, Parasitology, Cellular biology
Techniques/Expertise
Various bioinformatic methods are used to screen for promising drug targets and molecular biological and cell biological methods (confocal and electron microscopy with transgenic parasites) as well as in vitro parasite culture to characterise and test potential parasite drug targets. In collaboration with fellow Bio21 researcher, Professor Malcolm McConville, the group’s research is subjecting malaria parasites to metabolomic analyses to help understand the modes of action of existing and novel anti-malarial drugs.
Disease Models
Malaria
Genetically Modified Organisms
Plasmodium falciparum
