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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Prof Alister Ward

Dr Boris Novakovic

Prof Stephen Kent

Dr Jim Harris

Prof Jian Li

Dr Marina Harper

Dr Bernadette Jones-Freeman

Prof Tim Stinear

A/Prof Dena Lyras

Adjunct Prof Kathryn Holt

Ms Madeleine Wemyss

Miss Vik Ven Eng

Dr Wenyi Li

Dr Prasad Paradkar

A/Prof Anna Coussens

Prof Paul Hertzog

Prof Steven Gerondakis

Prof Ana Traven

Dr Kate Jeffrey

Miss Alessandra Gatta

Ms Caitlin Rowe

Dr Niamh Mangan

A/Prof Motti Gerlic

Miss Cassandra Stanton

Dr Kristie Jenkins

Miss Michelle Clark

Dr Grant Jenkin

Dr Thomas Angelovich

Dr Tom Brodnicki

Dr Jiyao Gan

Dr Douglas Gaskarth

A/Prof Aaron Irving

A/Prof Mark Wright

Dr Sammy Bedoui

Dr Latasha Abeynaike

Prof Bryan Williams

Associate Professor Michelle Tate

Dr Le Son Tran

Miss Rachel Webb

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Prof Roger Nation

Dr KE TANG

Dr Greg Moseley

Dr Rebecca Gorrell

Mrs Sheila Nankoberanyi

Dr Rhys Allan

A/Prof Mark Chong

Dr Tony Sadler

Prof Stephen Turner

Ms Alexandra Smith

Dr Matt Firth

Ms Sarah Rosli

A/Prof Michael Gantier

Dr Hani Hosseini Far

Dr Carla Bianca Victorio

Miss Rachel Peiris

Prof Gabrielle Belz

Ms Antara Ghoshal

Prof Bill Heath

Dr Ashraful Haque

Prof Jason Mackenzie

Dr Kelly Wyres

Dr Holly Anderton