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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Carla Bianca Victorio

Dr Seth Masters

Dr Boris Novakovic

Dr Rebecca Gorrell

Prof A Richard Kitching

Prof Di Yu

Dr Alice West

Dr Dominic De Nardo

Prof Bryan Williams

Dr Simon Royce

Dr Latasha Abeynaike

Prof Alister Ward

Miss Cassandra Stanton

Miss Rachel Peiris

Dr Scott Mueller

Dr Jiyao Gan

Prof Fabienne Mackay

A/Prof Dena Lyras

Dr Louis Schofield

Prof Paul Hertzog

Dr Bernadette Jones-Freeman

Dr Patrick Reading

Dr Kate Jeffrey

Prof Steven Gerondakis

A/Prof Michael Gantier

Dr Nicole De Weerd

Dr Helen Stoelting

Prof Jason Mackenzie

Miss Vik Ven Eng

A/Prof Motti Gerlic

Dr KE TANG

Dr Greg Moseley

Dr Rhys Allan

A/Prof Mark Wright

Dr Kristie Jenkins

Prof Jian Li

A/Prof Aaron Irving

Dr Ben Croker

Ms Sarah Rosli

Miss Michelle Clark

Dr Holly Anderton

Dr Hani Hosseini Far

Prof Tim Stinear

Dr Dieter Bulach

Prof Michael Hickey

Dr Prasad Paradkar

A/Prof Kumar Visvanathan

Ms Madeleine Wemyss

Prof Roger Nation

Dr Sara Klose

Dr Tony Sadler

Dr Kelly Wyres

Dr Marina Harper

Dr Niamh Mangan

Miss Kathryn Prame Kumar

Dr Catherine Kennedy

Dr Thomas Angelovich

Prof Stephen Turner

Prof Ana Traven

Prof Gabrielle Belz

Prof Bill Heath

A/Prof Ashley Mansell

Dr Alyssa Barry