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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Alice West

Prof Michael Hickey

Dr Tony Sadler

A/Prof Michael Gantier

Ms Madeleine Wemyss

Miss Alessandra Gatta

Prof A Richard Kitching

Prof Stephen Turner

Prof Paul Hertzog

Dr Kate Jeffrey

Dr Kelly Wyres

Prof Stephen Kent

Dr Thomas Angelovich

Ms Antara Ghoshal

Prof Ana Traven

Dr Alec Drew

Prof Di Yu

Miss Kathryn Prame Kumar

Prof Gabrielle Belz

A/Prof Motti Gerlic

Dr Sara Klose

Ms Alexandra Smith

Dr Scott Mueller

Dr Douglas Gaskarth

Dr Alyssa Barry

Dr Sammy Bedoui

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Dr Grant Jenkin

Dr Rutger Roring

A/Prof Mark Wright

Prof Alister Ward

Mrs Sheila Nankoberanyi

Dr Ben Croker

Miss Rachel Peiris

Dr Niamh Mangan

A/Prof Kumar Visvanathan

Prof Roger Nation

Dr Ashraful Haque

Dr Bernadette Jones-Freeman

Dr Patrick Reading

Dr Carla Bianca Victorio

Miss Cassandra Stanton

Dr Jim Harris

Dr Tom Brodnicki

A/Prof Dena Lyras

Dr Kristie Jenkins

Dr Holly Anderton

Adjunct Prof Kathryn Holt

Dr Seth Masters

Dr Louis Schofield

Dr Wenyi Li

Dr Marina Harper

Dr Rhys Allan

Dr Prasad Paradkar

Dr KE TANG

Dr Le Son Tran

Associate Professor Michelle Tate

A/Prof Ashley Mansell

Prof Bill Heath

Miss Vik Ven Eng

Dr Matt Firth

Prof Steven Gerondakis

A/Prof Aaron Irving