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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Mrs Sheila Nankoberanyi

Dr Nicole De Weerd

Dr Grant Jenkin

A/Prof Mark Chong

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Prof Roger Nation

Dr Dieter Bulach

Dr Scott Mueller

Miss Rachel Webb

Dr Rutger Roring

Dr Amy Chung

Dr Holly Anderton

Dr Niamh Mangan

Dr Helen Stoelting

Dr Boris Novakovic

Dr Thomas Angelovich

Miss Dianne Xu

Ms Antara Ghoshal

Dr Rhys Allan

Dr Douglas Gaskarth

Miss Cassandra Stanton

Dr Sammy Bedoui

Associate Professor Michelle Tate

Miss Michelle Clark

Ms Caitlin Rowe

Miss Rachel Peiris

Dr Jim Harris

Dr Prasad Paradkar

A/Prof Dena Lyras

Dr Matt Firth

Dr Marina Harper

Dr Rebecca Gorrell

Dr Hani Hosseini Far

Prof Stephen Kent

Dr Louis Schofield

Dr Latasha Abeynaike

Adjunct Prof Kathryn Holt

Prof Gabrielle Belz

Miss Vik Ven Eng

A/Prof Ashley Mansell

Prof Bryan Williams

Dr Greg Moseley

Prof Ana Traven

Prof A Richard Kitching

Prof Steven Gerondakis

Dr Kelly Wyres

Dr Alison West

Ms Madeleine Wemyss

Dr Alyssa Barry

Dr Wenyi Li

Dr Sara Klose

A/Prof Michael Gantier

Prof Stephen Turner

Ms Sarah Rosli

A/Prof Anna Coussens

Dr Alice West

Prof Alister Ward

Prof Di Yu

A/Prof Mark Wright

Prof Fabienne Mackay

Dr Ben Croker

Dr Jiyao Gan

Miss Kathryn Prame Kumar